Estradiol Cypionate API rau Preclinical R & D|Ntev-Kev Ua Haujlwm Txhawb Nqa-Tshuaj Estrogen Raw Khoom|Pharmaceutical-Qib Estradiol Cypionate rau Oral & Injectable Formulation Development
Cov ntsiab lus tseem ceeb
Ntev - ua yeeb yam txhawb nqa - tso cov khoom siv tshuaj estrogen|ruaj khov siab -purity profile|GMP-ua raws li kws tshuaj- qib estrogen API|nruj impurity tswj|Batch-rau-batch sib xws thiab traceability
Product Overview
Estradiol Cypionate API rau kev tshawb fawb preclinical thiab ntev -kev tsim cov tshuaj estrogen formulation yog ib tug hluavtaws cypionate ester derivative ntawm estradiol, thiab yog ib tug dav siv tshuaj - qib sustained - tso cov tshuaj estrogen raw khoom haum rau HRT cov kev tshawb fawb, thiab cov khoom siv raw khoom; kev tswj kev sim.
Cov tshuaj no -qibEstradiol Cypionate hmoovyog tsim los siv cov tshuaj synthesis siab heev thiab purification technologies, featuring ib tug ruaj khov molecular qauv thiab sustained - tso tawm yam ntxwv.Nws yog dav siv nyob rau hauv preclinical R & D, ntev - ua qauv tsim, kev tshawb fawb endocrine, thiab kev tsim tshuaj nruab nrab. Peb nruj me ntsis ua raws li GMP cov khoom siv raw khoom tsim cov qauv, nrog kev tswj xyuas nruj ntawm cov hlau hnyav, cov kuab tshuaj seem, thiab cov khoom muaj feem xyuam. Cov khoom lag luam ua kom pom cov khoom zoo sib xws thiab tuaj yeem ua tau raws li qhov xav tau ntawm cov chaw tshawb fawb txawv teb chaws, cov tuam txhab tshuaj, thiab cov neeg lag luam tshuaj zoo nrhiav kev siab - zoo ntev - ua cov tshuaj estrogen API raw khoom.
COA
| Yam khoom | Specification | Kev tshwm sim | |
| Yam ntxwv | Cov khoom no yog cov hmoov dawb los yog yuav luag dawb crystalline hmoov | Dawb hmoov | |
| Kev txheeb xyuas | A: IR B: HPLC | Ua raws | |
| Solubility | Insoluble hauv dej, soluble hauv cawv, hauv acetone, hauv chloroform thiab hauv dioxane; sparingly soluble hauv cov roj zaub. | Ua raws | |
| Melting ntau | 149 ~ 153 degree | 150.3 ~ 151.8 degree | |
| Kev sib hloov kho qhov muag tshwj xeeb | +39 ~ +44 degree | +40.8 degree | |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.05% | |
| Residuc ntawm ignition | Tsawg dua lossis sib npaug li 0.10% | 0.07% | |
| Assay | 97.0~103.0% | 99.69% | |
| Cov kuab tshuaj residual Methanol Methylene chloride |
Tsawg dua lossis sib npaug li 3000ppm Tsawg dua lossis sib npaug li 600ppm |
262 ppm ua Tsis pom |
|
| Particle loj | 100% Tsawg dua lossis sib npaug li 20μm | 100% Tsawg dua lossis sib npaug li 20μm | |
| Xaus | Cov khoom ua raws li cov cai ntawm USP Standard. | ||
Mechanism ntawm Action
Estradiol Cypionate hmoov,raws li ntev - ua yeeb yam tshuaj estrogen prodrug rau preclinical R&D, yog hydrolyzed nyob rau hauv vivo tso tawm nquag 17 -estradiol, muab cov tshuaj estrogen muaj nyob rau hauv kev tshawb fawb HRT, kev tshawb fawb endocrine, thiab kev tsim kho. Tom qab nkag mus rau hauv lub cev, nws yog hydrolyzed los ntawm esterases tso tawm active estradiol.
Estradiol tshwj xeeb khi rau cov tshuaj estrogen receptors (ER thiab ER), yog li tswj cov cell proliferation, sib txawv, thiab metabolic kev ua si los ntawm kev hloov pauv ntawm cov noob qoob loo thiab cov protein qhia.
Cov pab pawg cypionate tau txhim kho lipophilicity thiab ua kom ntev hauv vivo ib nrab -lub neej, ua kom ntev - tso tawm. Nws muab cov tshuaj estrogen tso tawm thaum txo qis cov tshuaj plasma hloov pauv hauv cov kev tshawb fawb preclinical cuam tshuam nrog luv luv - ua yeeb yam tshuaj estrogen. Qhov no ua rau nws haum rau ntev - kev siv tshuaj tiv thaiv cov tshuaj hormones, thiab nws cov txheej txheem ntawm kev ua tau zoo raws li kev lees paub thoob ntiaj teb cov qauv endocrinology.
Cov khoom siv
Daim ntawv thov ntawm Estradiol Cypionate Powder rau Preclinical R&D thiab Ntev -Kev Txhim Kho Kev Ua Haujlwm:
1. Raw khoom rau ntev - ua qhov ncauj thiab roj -raws li txhaj tshuaj formulations nyob rau hauv preclinical kev tshawb fawb
2. HRT-Txoj kev tshawb fawb txog tshuaj, kev tshuaj ntsuam xyuas, thiab kev ntsuas kev ruaj ntseg
3. Cov ntaub ntawv tshawb fawb txog endocrinology, tshuaj tua kab mob, thiab kev tshawb fawb tshuaj
4. Pharmaceutical intermediate rau sustained - tso tshuaj estrogen thiab endocrine - cov qauv kev cai
5. Kev lag luam tawm txawv teb chaws, kev lag luam tshuaj lom neeg zoo, thiab kho R & D khoom
Cov lus qhia ntxaws
Raws li physiological mechanism ntawm kev ua estrogen,Estradiol Cypionate hmoovtso tawm estradiol tom qab hydrolysis hauv vivo thiab tuaj yeem ua rau cov teebmeem hauv qab no ntawm lub cev. Tag nrho cov lus piav qhia yog kev txhawb nqa los ntawm cov txheej txheem endocrinology yam tsis muaj kev lees paub ntau dhau:
1. Txhawb cov tshuaj estrogen supplementation thiab preclinical endocrine R&D: Pab txhim kho endocrine imbalance txuam nrog tsawg estrogen theem thiab muab ruaj khov ntev - ua estrogen txhawb rau kev tshawb fawb formulation.
2 .Ntev- ua haujlwm txhawb nqa estrogen hauv kev tshawb fawb preclinical: Tswj cov kev ua haujlwm ntawm lub cev ntawm cov menyuam yaus, pob txha, tawv nqaij, thiab cov hlab plawv cov ntaub so ntswg hauv kev txhawb nqa - tso tawm cov kev tshawb fawb.
3. Pab tswj cov lipid metabolism thiab tswj kev noj qab haus huv lipid profiles, txhawb vascular endothelial noj qab haus huv.
4. Kev tswj cov pob txha metabolism rau preclinical R&D: Txo cov calcium poob, tswj cov pob txha ceev, thiab txhawb nqa ntev -cov kev sim endocrine.
5. Endocrine axis stabilization nyob rau hauv cov kev tshawb fawb formulation: Txhawb HRT thiab ntev -acting hormone tswj R&D.
Core Zoo
1. Ntev-Ua Kev Ncaj Ncees-Tshwj xeeb cov khoomCov qauv ester daim ntawv cog lus qeeb qeeb metabolic tso tawm, muab lub sijhawm ntev ntawm kev ua haujlwm thiab ruaj khov plasma concentrations, yog li txo qhov kev hloov pauv los ntawm kev tswj hwm ntau zaus.
2. Tswj Purity thiab impuritiesHPLC purity tseem nyob ruaj khov ntawm Ntau dua lossis sib npaug li 99.0%, thaum cov khoom muaj feem xyuam, cov kuab tshuaj seem, thiab cov hlau hnyav raug tswj nruj kom ua tau raws li cov khoom siv raw khoom txawv teb chaws.
3. Zoo heev Batch ConsistencyStandardized synthesis thev naus laus zis ua ke nrog tag nrho - txheej txheem tswj kev ua tau zoo txo qis cov cuab yeej physicochemical thiab purity variations ntawm batches, ua rau nws haum rau loj -scale kws tshuaj formulation manufacturing.
4. Kev Pabcuam Ua Raws Li Kev PabcuamCov khoom no yog npaj rau tib neeg kev tshawb fawb tshuaj thiab kev tsim khoom siv. Ua kom tiav cov ntaub ntawv txhawb nqa kev lis kev cai txawv teb chaws thiab tshuaj xyuas kev tsim nyog.
5. Customized Supply ServicesTxhawb me me - ntsuas cov qauv xaj thiab cov khoom siv ntau. Cov ntaub ntawv ntim thiab cov ntawv xeem tuaj yeem kho raws li cov neeg siv khoom tuaj txawv teb chaws nyiam.
Quality Assurance
1. Ua los ntawm kev siv tshuaj- qib pib cov ntaub ntawv hauv GMP-cov chaw huv huv raws li kev tswj hwm kev tsim khoom
2. Txhua batch tau txais kev ntsuam xyuas zoo, suav nrog HPLC kev tshuaj ntsuam xyuas, cov ntsiab lus melting, cov ntsiab lus noo noo, cov hlau hnyav, thiab cov khoom muaj feem xyuam, nrog rau COA cov ntaub ntawv soj ntsuam zoo.
3. Tag nrho cov ntaub ntawv, cov txheej txheem ntau lawm, thiab batch traceability cov ntaub ntawv muaj nyob rau kom txaus siab rau txawv teb chaws kev lis kev cai thiab buyer tsim nyog xyuas
4. Cov qauv kuaj tau txais kev txhawb nqa, thiab cov khoom lag luam loj tseem zoo ib yam nrog cov qauv zoo los xyuas kom muaj kev ruaj ntseg.
FAQ
Q1: Cov khoom no puas tuaj yeem siv ncaj qha los ntawm tib neeg?
A: Qhov no ntev - ua yeeb yamEstradiol Cypionate hmoovyog ib qho tshuaj raw khoom thiab yuav tsum tsis txhob noj ncaj qha los yog txhaj tshuaj. Nws yuav tsum tau ua tiav rau hauv cov qauv tsim los ntawm cov tuam txhab tshuaj lossis cov chaw tshawb fawb raws li cov txheej txheem tsim khoom. Kev siv ncaj qha los ntawm tib neeg tsis pom zoo.
Q2: Ua li cas Estradiol Cypionate txawv ntawm estradiol li niaj zaus hauv lub sijhawm ua haujlwm?
A: Qhov no txhawb nqa - tso tawm Estradiol Cypionate Powderestrogen raw cov ntaub ntawv yog lub sijhawm ntev - ua haujlwm ruaj khov - tso cov tshuaj estrogen prodrug nrog ntev dua nyob rau hauv vivo ib nrab - lub neej thiab ruaj khov plasma concentrations. Nws lub sijhawm ua haujlwm yog ntev dua li luv luv - ua yeeb yam estradiol thiab tsis tas yuav siv sijhawm ntau.
Q3: Dab tsi ntawm cov formulations yog cov khoom siv raw rau?
A: Nws yog qhov tsim nyog rau kev txhim kho ntev ntev - roj ua yeeb yam - raws li kev txhaj tshuaj, txhawb nqa - tso tawm cov tshuaj hormones, thiab endocrine- kev tswj cov tshuaj formulations, nrog rau kev paub tab thiab ruaj khov daim ntawv thov scenarios.
Q4: Dab tsi yog qhov txawv ntawm Estradiol Cypionate thiab Estradiol Valerate?
A: Estradiol Cypionate muaj lipophilicity siab dua thiab qeeb qeeb metabolic tso tawm, ua rau muaj kev tshaj tawm ntev dua - ua haujlwm ruaj khov - tso tawm cov nyhuv, ua rau nws tsim nyog rau ultra- ntev - lub voj voog cov tshuaj hormones - kev tswj kev tsim kho.
Hoobkas
Daim ntawv pov thawj
Shipping & Packing
Tiv tauj peb rau kev yuav khoom|Kev txhawb nqa & Kev xa khoom sai
Estradiol Cypionate hmoovrau preclinical R&D thiab ntev -kev txhim kho tshuaj estrogen formulation yog muaj nyob thoob ntiaj teb rau HRT cov kev tshawb fawb, tshuaj formulation kev loj hlob, thiab endocrine- kev tshawb fawb kev cai, muab ruaj khov thiab raws li raw cov ntaub ntawv ua ke nrog ib tug -tawm procurement kev daws teeb meem rau txawv teb chaws kws tshuaj, cov chaw tshawb fawb, thiab cov lag luam tshuaj zoo.Ob qho piv txwv xaj thiab kev yuav khoom ntau tuaj yeem ua tiav nrog kev xa khoom sai thiab ua tiav tom qab- kev txhawb nqa kev muag khoom.
Rau cov ncauj lus kom ntxaws cov ntaub ntawv zoo, qauv hais, los yog customized ntim cov kev daws teeb meem, xav tiv tauj peb.
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Cim npe nrov: Tuam Tshoj estradiol cypionate hmoov manufacturers, lwm tus neeg, Hoobkas
