17 -Estradiol Powder CAS 57-91-0|High-Purity Ntau dua lossis sib npaug rau 99% Steroid Estrogen rau Preclinical R & D & Pharmaceutical Formulation Development
Cov ntsiab lus tseem ceeb
Siab -Purity Ntau dua lossis sib npaug li 99% (HPLC)|17 -Stereoisomer Estrogen|Kev Tshawb Fawb & Pharmaceutical Qib|Ruaj khov Physicochemical Properties|USP/EP Ua Raws|Ua kom tiav cov ntaub ntawv & Kev xa khoom ruaj khov thoob ntiaj teb
Product Overview
17 -Estradiol( -stereoisomer ntawm estradiol) yog siab -purity steroid estrogen rau kev tshawb fawb ua ntej, R&D, thiab kev tsim kho tshuaj. Nws muaj qhov tshwj xeeb stereochemistry, ruaj khov physicochemical zog, thiab tswj cov impurities nruj me ntsis, ua rau nws zoo tagnrho rau endocrine mechanism kev tshawb fawb, cell-raws li kev sim, analytical calibration, thiab kuaj kuaj.
Cov khoom no siab -purity raw khoom yog muab los ua cov hmoov dawb crystalline hmoov, tsis muaj ntxhiab tsw, nrog cov khoom ruaj khov physicochemical thiab nruj tswj cov impurities. Nws yog dav siv nyob rau hauv kev tshawb fawb tshuaj, endocrine mechanism kev tshawb fawb, lub neej science thwmsim, analytical calibration, thiab formulation txoj kev loj hlob.
Ua los ntawm kev siv ntau-qib purification thiab qib siab synthesis, qhov siab -purity 17 -Estradiol hmoov ua kom batch- rau-batch sib xws thiab zoo heev solubility nyob rau hauv cawv thiab ketones, haum rau formulation soj ntsuam, preclinical kev tshawb fawb, thiab bulk laboratory procurement.Muaj rau kev yuav khoom thoob ntiaj teb.
COA
| Yam khoom | Specification | Kev tshwm sim | |
| Qhov tshwm sim | Dawb los yog dawb crystalline hmoov. | Ua raws | |
| Kev txheeb xyuas | A: IR | Ua raws | |
| Solubility | Soluble hauv ethyl cawv, acetone; me ntsis soluble hauv ether thiab chloroform; insoluble hauv dej | Ua raws | |
| Melting ntau | 223.0 ~ 229.0℃kub | 223.1 ~ 224.4℃kub | |
| Kev sib hloov tshwj xeeb | +51.0℃~ +56.0 degree | +53.2 degree | |
| Hais txog yam khoom Txhua tus neeg impurity Tag nrho impurities |
Tsawg dua lossis sib npaug li 0.2% Tsawg dua lossis sib npaug li 1.0% |
0.13% 0.28% |
|
| Poob rau ziab | Tsawg dua lossis sib npaug li 3.0% | 0.52% | |
| Cov kuab tshuaj residual Ethyl acetate hmoov Ethyl cawv |
Tsawg dua lossis sib npaug li 5000 PPm Tsawg dua lossis sib npaug li 5000 PPm |
8 20 ppm 160 ppm ib |
|
| Assay | 97-103%(C18H24O2) | 99.80% | |
| Xaus | Cov khoom ua raws li cov cai ntawm USP Standard. | ||
Mechanism ntawm Action
17 -Estradiol Hmoov rau preclinical R & D xaiv khi cov tshuaj estrogen receptor subtypes, modulating noob qhia, hormone signaling, thiab metabolic regulation. Nws qhov tshwj xeeb stereochemistry txawv nws los ntawm 17 -Estradiol, ua rau nws tsim nyog rau kev tshawb fawb txog endocrine mechanism, tshuaj xyuas cov tshuaj validation, thiab steroid optimization thwmsim.Mechanism Highlights:
● Txhawb estrogen supplementation thiab endocrine mechanism R&D
● Tswj cov cell proliferation, sib txawv, thiab cov txheej txheem metabolic hauv cov qauv preclinical
● Ua kom yooj yim rau steroid pharmacology, receptor selectivity kev tshawb fawb, thiab kev siv tshuaj lub hom phiaj
Cov khoom siv
1. Kev Tshawb Fawb & Kev Tshawb Fawb17 -Estradiol yog ib qho kev tshawb fawb zoo tshaj - cov khoom siv tshuaj estrogen. Piv nrog rau 17 -Estradiol, nws muaj zog estrogenic kev ua si tab sis zoo heev los tiv thaiv- laus thiab neuroprotective teebmeem, dav siv hauv kev laus, neurobiology, oxidative stress thiab metabolic mechanism tshawb fawb.
2. Anti-Kev laus & Kev Txhim Kho NeuroprotectionNws yog siv rau kev tshawb fawb thiab kev loj hlob ntawm anti-aging thiab neuroprotective pharmaceuticals. Nws tuaj yeem txo cov kab mob neuroinflamation, tiv thaiv cov paj hlwb thiab txhim kho lub hnub nyoog - cuam tshuam txog kev paub tsis meej, ua cov khoom siv tseem ceeb rau kev txhim kho kev laus los tiv thaiv -.
3. Kev tshawb fawb Metabolic & EndocrineQhov API no feem ntau siv rau hauv kev tshawb fawb endocrine thiab metabolic, suav nrog kev tswj cov piam thaj thiab lipid metabolism. Nws txhawb txoj kev tshawb fawb ntawm cov tshuaj estrogen subtypes 'kev cuam tshuam rau tib neeg cov metabolism thiab cuam tshuam cov kab mob metabolic.
4. Pharmaceutical Intermediate & FormulationNrog siab purity thiab ruaj khov zog, 17 -Estradiol ua raws li ib tug kws steroid intermediate rau synthesis thiab zus tau tej cov tshuaj estrogen tshwj xeeb npaj.
Cov lus qhia ntxaws
● Preclinical endocrine mechanism kev tshawb fawb: 17 stereochemistry tso cai rau kev kawm xaiv cov tshuaj estrogen receptor subtypes, hormone signaling pathways, thiab metabolic regulation.
● Preclinical SAR cov kev tshawb fawb piv 17 - vs 17 -Estradiol: tuaj yeem muab piv nrog 17 -Estradiol rau cov tshuaj molecular stereochemistry thiab bioactivity tsom xam, txhawb kev tshuaj xyuas tshuaj txhuas.
● Cell-raws li kev tshawb fawb tshuaj thiab tshuaj xyuas lub hom phiaj: tswj kev loj hlob thiab kev sib txawv ntawm cov qauv ntawm tes, tsim nyog rau kev tshawb fawb tshuaj thiab tshuaj xyuas lub hom phiaj.
● Laboratory calibration thiab analytical standard R&D: High-purity and conformity, zoo tagnrho rau kev kuaj tshuaj hormones, chromatography, thiab kuaj kom zoo.
● Preclinical formulation and process optimization studies: Stable physicochemical properties support formulation stability testing, excipient compatibility, thiab cov txheej txheem optimization.
Core Zoo
● High-purity 17 -Estradiol rau preclinical R&D thiab kev siv tshuaj: HPLC purity Ntau dua los yog sib npaug li 99%, nrog nruj tswj cov kuab tshuaj residual, hnyav hlau, thiab impurities; zoo tagnrho rau cov kev sim kuaj xyuas meej thiab tsim qauv tsim.
● Stable 17 Stereochemistry: Resistant rau oxidation thiab ya raws, ua kom muaj kev rov tsim dua tshiab hauv kev tshawb fawb txog kev kho mob thiab tshuaj.
● Broad Solubility Compatibility: Soluble hauv cawv thiab ketones; adaptable rau formulation R & D, chromatographic nrhiav kom tau, thiab kuaj kev tshawb fawb daim ntaub ntawv.
● Kev xa khoom yooj yim & Kev xa khoom thoob ntiaj teb: Txhawb nqa 10g qauv xaj, me me - cov khoom nruab nrab, thiab tuj- theem ntev - cov ntawv cog lus; ceev ceev nrog thoob ntiaj teb logistics.
● Kev Pabcuam Kev Lag Luam.
Quality Assurance
● Ntau-Qhib QC: HPLC purity, muaj feem xyuam rau, thiab physicochemical pov thawj rau txhua batch; tag nrho traceable.
● GMP-Ua raws Kev Tsim Khoom: Ua raws li GMP thiab ISO9001 cov qauv; ua raws li USP/EP cov lus qhia.
● Ua tiav Cov Ntaub Ntawv: COA, HPLC spectra, MSDS, TDS; txhawb nqa thib peb- tog neeg pov thawj thiab kev tswj hwm kev ua raws cai.
● Tag Nrho Traceability: Raw khoom procurement, synthesis, purification, thiab tiav cov khoom shipping raug saib xyuas kom paub meej batch sib xws.
FAQ
Q1: Dab tsi yog cov ntawv thov ntawm 17 -Estradiol hmoov?
A: Kev tshawb fawb hauv cov txheej txheem endocrine, kev tsim tshuaj tshiab, kev ntsuas ntsuas ntsuas, thiab kev kawm kev kawm.
Q2: Dab tsi yog 17 -Estradiol hmoov siv rau?
A: Nws yog dav siv rau kev tshawb fawb txog endocrine mechanism, kev tsim tshuaj tshiab, kev ntsuas ntsuas ntsuas, thiab kev sim kev kawm. Nws tseem tuaj yeem ua tus qauv siv rau kev tshuaj ntsuam xyuas thiab qauv- kev tshawb fawb txog kev sib raug zoo.
Q3: Puas yog 17 -Estradiol hmoov tuaj yeem siv ncaj qha rau hauv cov tshuaj formulations?
A: Yog lawm, nws tuaj yeem siv los ua cov khoom siv raw hauv chav kuaj R & D thiab cov kev tshawb fawb ua ntej, txhawb kev tsim kho, kev ntsuas kev ruaj ntseg, thiab kev npaj tshuaj ntsuam xyuas.
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Shipping & Packing

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Kev txiav txim17 -Estradiolhmoov rau preclinical R & D, tshuaj formulation kev loj hlob, thiab kev soj ntsuam kev soj ntsuam nrog tej kev xaiv yuav khoom, sib tw nqi, thiab xa ceev ceev mus rau thoob ntiaj teb kev lag luam. Cov qauv dawb, COA cov ntaub ntawv, thiab kev txhawb nqa yog muaj los ntawm tus neeg muag khoom txhim khu kev qha.
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