Alexamorelin hmoov

Alexamorelin hmoov CAS 196808-85-2|Loj hlob Hormone Secretagogue Peptide Chaw Muag Khoom Tuam Tshoj|Ntau dua lossis sib npaug li 98% HPLC

Core Muag Cov Ntsiab Lus

✅ Ntau dua lossis sib npaug li 98% HPLC Purity: Siab -purity Alexamorelin hmoov ua kom ntseeg tau cov ntaub ntawv receptor khi.

✅ D-Amino Acid Stability: Kev koom ua ke ntawm D-2-Nal thiab D-Phe muab kev tiv thaiv zoo rau enzymatic degradation.

✅ Muaj Peev Xwm GHS: Tsim los rau kev tshawb fawb tsom rau ghrelin receptor (GHS{0}}R1a) kom muaj zog GH tso tawm.

✅ Tuam Tshoj Peptide Chaw Tsim Tshuaj: GMP- ua raws cov txheej txheem tsim khoom nrog cov kws tshaj lij hauv kev tshwj xeeb hydrophobic amino acid coupling.

✅ Kev Tshawb Fawb Txog Kev Tshawb Fawb Tag Nrho: Tus neeg pov thawj pom zoo los ntawm siab - daws teeb meem LC-MS; purity paub tseeb los ntawm HPLC.

✅ Kev Siv Tau yooj yim: Kev txhawb nqa rau milligram cov qauv tshawb fawb txog li kilogram - nplai xaj ntau.

Alexamorelin hmoovyog ib qho hluavtaws hexapeptide kev loj hlob hormone secretagogue (GHS). Nws belongs rau Growth Hormone Releasing Peptide (GHRP) tsev neeg thiab ua raws li lub zog agonist ntawm ghrelin receptor. Structurely, nws yog qhov txawv los ntawm lub xub ntiag ntawm D-2-naphthylalanine (D-2-Nal) nyob rau hauv lub thib ob txoj hauj lwm, uas pab txhawb rau nws siab affinity thiab potency.

Hauv kev tshawb fawb ua ntej -kev tshawb fawb soj ntsuam, Alexamorelin qhia txog lub peev xwm los txhawb lub caj pas pituitary kom tso tawm cov tshuaj hormones loj hlob (GH) hauv ib koob tshuaj - nyob ntawm seb. Nws yog dav siv nyob rau hauv cov chaw kuaj mob los kawm cov hypothalamic-pituitary-somatotropic axis thiab tshawb nrhiav cov teebmeem metabolic ntawm ghrelin mimetics. HDM BIO muab cov khoom siab no -purity peptide rau cov pab pawg tshawb fawb thoob ntiaj teb thiab biotech.

Tshawb nrhiav-tsuas yog kev lees paub: Rau ua ntej- kuaj kuaj kuaj mob nkaus xwb. Tsis yog rau tib neeg siv tshuaj kho mob, kuaj mob, lossis tshuaj.

PebAlexamorelin hmoovkev tsim khoom ua raws li Fmoc tshwj xeeb-SPPS raws tu qauv:

• Tshwj xeeb Coupling: Siv siab -purity Fmoc-D-2-Nal-OH lub tsev thaiv nrog optimized coupling sij hawm los xyuas kom meej 100% hloov dua siab tshiab ntawm bulky naphthyl pawg.
• Stepwise Assembly: Precise elongation of the hexapeptide chain on a Rink Amide resin to yield the C-terminal amide.
• Acid Cleavage: Cov kev mob me me los tiv thaiv Trp (Tryptophan) residue los ntawm oxidation.
• RP-HPLC Purification: Preparative thim rov qab-theem HPLC tshem tawm cov ntu ntu thiab diastereomeric impurities.
• Kev Tshaj Tawm Zoo: Kev sim zaum kawg siv LC-MS thiab HPLC kom ua tau raws li Cov Txheej Txheem Zoo Tshaj los yog sib npaug rau 98% purity tus qauv.

Hydrophobic impurity tswj

Lub xub ntiag ntawm ntau lub nplhaib uas muaj ntxhiab (Nal, Trp, Phe) ua rau Alexamorelin hydrophobic heev. Peb lub tswv yim purification zoo tshem tawm cov seem hydrophobic tiv thaiv pawg tawg thiab cov khoom oxidation.

HDM BIO muab kev tshawb fawb-qib Abaloparatide hmoov rau chav kuaj thiab ua ntej- cov ntawv kho mob nkaus xwb.

1. D-Amino Acid Integrity: Kev txheeb xyuas ntawm D-isomer purity los tiv thaiv tsis ua haujlwm L- isomer paug.
2. Kev Tiv Thaiv Tryptophan: Ua kom ntseeg tau tias Trp residues tsis oxidized thaum lub sij hawm sib txuas thiab khaws cia.
3. Analytical Transparency: Muab tag nrho HPLC thiab MS chromatograms rau txhua pawg.
4. Supply Chain Stability: Txhim khu kev xa khoom ntawm D-2-Nal lub tsev thaiv rau kev tsim khoom loj.

• MOQ: Yooj yim; milligram cov qauv thiab ntau gram- nplai xaj muaj.
• Cov qauv: them cov qauv kuaj muaj nrog tag nrho cov ntaub ntawv QC.
• Bulk pricing: Tiered pricing qauv raws li kev txiav txim ntim.
• Lub Sijhawm Lead: Cov txheej txheem txheej txheem feem ntau yog nyob rau hauv Tshuag; kev cai txiav txim nkoj hauv 2-3 lub lis piam.
• Nqe Lus Nug: Hu rau peb pab neeg muag khoom rau cov lus tshaj tawm tshiab raws li koj qhov kev xav tau purity tshwj xeeb.

1. GHS-R1a Receptor Signaling: Kawm txog kev ua kom muaj kev loj hlob hormone secretagogue receptors.
2. Pituitary Hormone Regulation: Tshawb xyuas cov txheej txheem ntawm GH tso tawm thiab somatotropic signaling.
3. Kev Tshawb Fawb Txog Metabolic: Tshawb nrhiav cov teebmeem ntawm ghrelin mimetics ntawm qab los noj mov, insulin rhiab heev, thiab lub cev muaj pes tsawg leeg.
4. Somatopause Studies: Ua ntej- kev soj ntsuam kev soj ntsuam hauv cov qauv kev laus uas cuam tshuam nrog kev loj hlob hormone poob.
5. GHS Structure-Kev Sib Raug Zoo: Sib piv qhov muaj zog thiab kev xaiv ntawm cov GHRPs sib txawv.

Q: CAS tus naj npawb ntawm Alexamorelin hmoov yog dab tsi?
A: CAS npe 196808-85-2.

Q: Puas yog Alexamorelin yog ghrelin mimetic?
A: Yog lawm, nws yog ib qho hluavtaws loj hlob hormone secretagogue uas ua raws li qhov kev txiav txim ntawm ghrelin.

Q: Kuv puas tuaj yeem yuav Alexamorelin hmoov los ntawm Tuam Tshoj?
A: HDM BIO yog cov kws tshaj lij peptide chaw tsim khoom muab siab -purity Alexamorelin thoob ntiaj teb.

Q: Yuav khaws cov hmoov li cas?
A: Khaws kaw ntawm -20 degree, tiv thaiv lub teeb thiab noo noo. D-amino acid peptides ruaj khov, tab sis Trp residues rhiab rau lub teeb / oxygen.

Q: Dab tsi yog qhov purity ntawm koj Alexamorelin?
A: Peb qhov kev tshawb fawb tus qauv- qib purity yog ntau dua lossis sib npaug li 98% HPLC.

Peb muab ib qho kev tshaj lij - nres kev yuav khoom thiab kev txhawb nqa rau ntiaj teb peptide R&D cov haujlwm:

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