Ziconotide hmoov CAS 107452-89-1|GMP Peptide Chaw tsim tshuaj paus Tuam Tshoj|Ntau dua lossis sib npaug li 98% HPLC

Core Muag Cov Ntsiab Lus

✅ Ntau dua lossis sib npaug li 98% HPLC Purity: Txhua pawg ntawm Ziconotide hmoov suav nrog cov ncauj lus kom ntxaws chromatogram.

✅ Precise Folding Control: Cov kws tshaj lij hauv kev tsim cov 1-16, 8-20, 15-25 disulfide choj qauv tseem ceeb rau kev ua haujlwm lom neeg.

✅ Tuam Tshoj Peptide Chaw Tsim Tshuaj: GMP- ua raws cov chaw tsim khoom tshwj xeeb hauv kev sib xyaw conotoxin.

✅ Kev Ntsuas Tus Kheej: Cov qauv kev ntseeg tau lees paub los ntawm LC-MS thiab amino acid tsom xam (AAA).

✅ Ua tiav Cov Ntaub Ntawv: Kev txhawb nqa tag nrho rau kev kuaj xyuas hauv chav kuaj, suav nrog MSDS thiab cov ntaub ntawv tshem tawm.

✅ Scalable Supply: Cov kev xaiv yooj yim los ntawm 1mg kev tshawb fawb vials rau ntau -gram bulk mov.

Ziconotide Powder yog dab tsi?

Ziconotide hmoovyog daim ntawv hluavtaws ntawm ωω-conotoxin MVIIA, 25-amino acid peptide keeb kwm pom nyob rau hauv cov venom ntawm marine snailConus magus. Raws li lub zog thiab xaiv N- hom voltage-gated calcium channel (VGCC) blocker, nws yog ib qho kev tshawb fawb tseem ceeb rau kev tshawb nrhiav tsis yog -opioid txoj hauv kev mob ntev thiab kev tiv thaiv neuroprotection.

Lub synthesis ntawm Ziconotide yog qhov nyuaj ntau dua li cov qauv linear peptides vim nws peb cov nyiaj hauv disulfide. Ntawm HDM BIO, peb siv optimized oxidative folding buffers thiab thermodynamic tswj los xyuas kom meej qhov tseeb "neeg" conformation. Peb cov txheej txheem minimizes misfolded isomers thiab truncated sequences, muab cov neeg soj ntsuam nrog zoo ib yam thiab bioactive peptide raw cov ntaub ntawv.

Tshawb nrhiav-tsuas yog kev lees paub: Rau ua ntej- kuaj kuaj kuaj mob nkaus xwb. Tsis yog rau tib neeg siv tshuaj kho mob, kuaj mob, lossis tshuaj.

Dab tsi yog Cov Lus Qhia Zoo ntawm Ziconotide hmoov?

Yam khoom	Specification	Kev tshwm sim
Qhov tshwm sim	Dawb rau tawm -dawb hmoov	Zoo ib yam
Purity (HPLC)	Ntau dua lossis sib npaug li 98%	99.96%
MS Identity	Raws li tus qauv siv	Kev lees paub
Xaus	Cosmetic raw khoom xav tau	Dhau

Ziconotide vs Lwm Conotoxins: Qhov txawv yog dab tsi?

Peptide	Kev xaiv	Tshawb fawb tsom	CAS Nr
Ziconotide	N-type (Caᵥ2.2) xaiv	Kev tshawb nrhiav mob hnyav	107452-89-1
ωω-Conotoxin GVIA	N-type (irreversible)	Calcium channel daim ntawv qhia	106362-34-9
μμ-Conotoxin GIIA	Muscle-hom Na⁺ channels	Neuromuscular signaling	93605-62-4

Ziconotide Ua li cas?

PebZiconotide hmoovmanufacturing txheej txheem hais txog cov txheej txheem precision:

Chain Assembly: Linear 25-mer sequence elongation via standardized Fmoc-SPPS.
Selective Cleavage: Maj mam resin cleavage khaws cia rau cysteine sab - chains nyob rau hauv lub xeev txo.
Oxidative Folding: Cov kauj ruam tseem ceeb - siv huab cua - oxidation los yog redox - tsis siv tshuab los tsav kev tsim ntawm peb tus choj tshwj xeeb disulfide.
Isomer Purification: Siv siab - daws teeb meem RP-HPLC los cais cov bioactive Ziconotide los ntawm misfolded isomers.
Kev Tshaj Tawm Zoo: Kev txheeb xyuas zaum kawg ntawm LC-MS kom paub meej qhov tseeb thiab HPLC kom paub meej.

Folding Integrity & Impurity Control

Kev tshawb fawb Ziconotide yuav tsum tau tshem tawm ntawm "scrambled" peptides (isomers nrog tsis raug disulfide khub). HDM BIO ntiav cov txheej txheem tsom xam los xyuas kom meej qhov kev ruaj ntseg ntawm cov thermodynamic thiab cov qauv zoo sib xws ntawm txhua pawg.

Qhov txawv ntawm Kev Tshawb Fawb Qib thiab Pharmaceutical Qib Ziconotide yog dab tsi?

Qeb	Qib tshawb fawb	Pharmaceutical Qib (API)
Lub Hom Phiaj	Preclinical lab tshawb fawb	Clinical tshuaj ntau lawm
Cov ntaub ntawv	COA / HPLC / LC-MS / MSDS	DMF / GMP Cov Ntaub Ntawv Ua Raws Cai
Daim ntawv thov	Hauv -vitro / Tsiaj qauv	Tib neeg intrathecal txhaj
Yam khoom	Tshawb nrhiav Peptide Supplier	Daim ntawv tso cai API Chaw tsim khoom

HDM BIO muab kev tshawb fawb-qib Ziconotide hmoov rau kev siv hauv chav kuaj thiab tsim R&D nkaus xwb.

Vim li cas tus neeg muab khoom tsim nyog tseem ceeb ua ntej yuav Ziconotide?

Ziconotide qhov ua tau zoo yog nyob ntawm nws cov qauv 3D. Ntsuas cov ntsiab lus no:

Folding Expertise: Tus neeg muag khoom puas muaj cov ntaub ntawv pov thawj kev tsim choj disulfide?
HPLC Resolution: Lawv txoj kev tshuaj ntsuam puas paub qhov txawv Ziconotide los ntawm nws cov isomers?
Batch Traceability: Tag nrho cov ntaub ntawv tsim tawm los ntawm amino acid coupling mus rau qhov kawg lyophilization.
Kev Pabcuam Kev Pabcuam: Muaj cov kws tshaj lij los tham txog kev solubility thiab kev ruaj ntseg hauv kev tshawb fawb buffers.

Ziconotide Powder Nqe & Daim Ntawv Qhia Ntau Yam 2026

MOQ: Yooj yim; milligram cov qauv thiab cov gram ntau ntau- nplai xaj tau txais kev txhawb nqa.
Cov Qauv: Cov qauv kuaj tau lees paub muaj nrog tag nrho QC cov ntaub ntawv.
Nqe: Tiered qauv raws li ntim. Kev sib tw quotes rau tsev kawm ntawv labs thiab biotech institutes.
Lub sij hawm xa tuaj: Feem ntau 1-2 lub lis piam rau cov khoom Tshuag; 3-4 lub lis piam rau loj kev cai synthesis.
Nqe Lus Nug: Hu rau peb pab neeg muag khoom kom tau txais kev tsocai raws li koj qhov kev xav tau purity thiab kom muaj nuj nqis.

Vim li cas thiaj xaiv HDM BIO ua koj tus neeg muag khoom?

Conotoxin Cov Kws Tshaj Lij: Kev paub ntau yam hauv ntau -cysteine peptide synthesis thiab folding.
Superior Purity Control: Advanced HPLC txoj hauv kev los xyuas kom muaj ntau dua lossis sib npaug li 98% purity, tsis pub muaj cov kab mob sib kis.
Cov Qauv Certainty: Txhua pawg tau txheeb xyuas tus kheej (LC-MS) thiab purity (HPLC).
GMP-Aligned Quality: nruj QC cov qauv tsim los ntawm kev tsim tshuaj.
Kev Ruaj Ntseg Hauv Ntiaj Teb: Kev paub txog kev xa khoom peptides nrog cov kev lis kev cai thiab cov ntaub ntawv kev nyab xeeb.

Dab tsi yog Daim Ntawv Thov Kev Tshawb Fawb Tseem Ceeb?

N- hom Calcium Channel Blocking: Kev tshawb fawb ntawm neurotransmitter tso tawm ntawm lub davhlau ya nyob twg presynaptic.
Tsis yog -Opioid Analgesic R&D: Tshawb nrhiav txoj hauv kev uas zam cov tshuaj opioid- cuam tshuam txog kev phiv.
Neuropathic Pain Models: Kev ntsuam xyuas hauv ntshav qab zib neuropathy lossis post-herpetic neuralgia qauv.
Kev xa tshuaj: Kev tshawb fawb txog kev txhawb nqa - tso cov twj tso kua mis lossis cov khoom nqa hydrogel.
Kev Tshawb Fawb Neuroprotection: Tshawb nrhiav VGCC inhibition hauv cov qauv kev raug mob ischemic.

Cov Lus Nug Txog Ziconotide Powder

Q: CAS tus lej ntawm Ziconotide yog dab tsi?
A: CAS Nr .: 107452-89-1.

Q: Koj lub Ziconotide puas muaj cov txuas txuas txuas ncaj qha?
A: Yog. Peb siv cov kev taw qhia folding thiab MS pov thawj los xyuas kom meej 1-16, 8-20, thiab 15-25 choj qauv.

Q: Kuv puas tuaj yeem yuav Ziconotide hmoov los ntawm Tuam Tshoj?
A: HDM BIO yog cov chaw tsim khoom hauv Suav teb uas muab siab -Ziconotide purity rau kev tshawb fawb thoob ntiaj teb.

Q: Dab tsi yog qhov pom zoo cia?
A: Khaws cov hmoov lyophilized ntawm -20 degree. Ib zaug reconstituted, aliquot thiab cia ntawm -80℃kom muaj kev ruaj ntseg.

Q: Kuv puas tuaj yeem xaj Ziconotide hauv ntau?
A: Yog, peb txhawb nqa kev txiav txim xws li milligrams rau kev tshawb nrhiav kev sim mus rau kilograms rau qhov loj R & D tej yaam num.