Trimethoprim Lactate API Chaw tsim tshuaj paus Tuam Tshoj|Ntau dua lossis sib npaug rau 98% DHFR Inhibitor Antibiotic Powder CAS 23256-42-0

Ntsiab Muag Khoom

✓ Dej-Soluble Trimethoprim ntsev - 20 mg/mL hauv dej (vs Dawb Base me ntsis Soluble)

✓ Zoo tagnrho rau Kev Txhaj Tshuaj & Cov Tshuaj Hauv Qhov Ncauj - Daim Ntawv Qhia Tshuaj Kho Mob

✓ Xaiv cov kab mob DHFR Inhibitor - Tib yam tshuaj tua kab mob ua dawb Trimethoprim

✓ Kub-Standard Sulfonamide Synergist - Sequential Folate Blockade (Bactericidal)

✓ Veterinary Injection Partner - Sulfadiazine/TMP (xws li Diatrim 200/40 mg/mL)

✓ Broad Gram-Positive & Gram-Negative Spectrum - Tsiaj Tsiaj & Tsiaj Tsiaj Kab Mob

Trimethoprim Lactate Powder yog dab tsi?

Trimethoprim Lactate hmoovyog cov dej -soluble lactate ntsev ntawm trimethoprim (TMP), ib tug hluavtaws diaminopyrimidine antibacterial - chemically 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine ua ke nrog lactic acid (C₁₄H₂, M₄4).

Nws qhov txiaj ntsig tseem ceeb tshaj li dawb trimethoprim yog qhov ua tau zoo ntawm cov dej solubility (~ 20 mg / mL vs me ntsis soluble), ua rau nws nyiam daim ntawv rau cov tshuaj tua tsiaj thiab cov kua hauv qhov ncauj. Nws yog dav formulated nrog sulfonamides - feem ntau sulfadiazine sodium (xws li Diatrim 200/40 mg/mL txhaj rau nyuj, npua, dev thiab miv) - thiab kuj nrog sulfadimethoxine thiab sulfamethoxazole. Antibacterial kev ua si zoo ib yam li dawb TMP: xaiv DHFR inhibition (~ 50,000-fold kab mob vs mammalian affinity), bacteriostatic ib leeg, bactericidal nrog sulfonamides ntawm sequential folate blockade. Siv rau kev ua pa, GI thiab urinary kab mob hauv cov tsiaj nyeg thiab cov tsiaj sib koom ua ke los ntawm cov kab mob uas muaj kab mob. Cov koob tshuaj ntau / ntev yuav ua rau tsis muaj folate (tswj tau nrog folic acid); co-trimoxazole cov teebmeem loj tshaj plaws yog sulfonamide ntsig txog.

Trimethoprim Lactate Powder ua haujlwm li cas?

Trimethoprim Lactate Powder exerts tib cov tshuaj tua kab mob zoo li dawb trimethoprim: xaiv, thim rov qab inhibition ntawm cov kab mob dihydrofolate reductase (DHFR), thaiv kev hloov pauv ntawm DHF rau THF - active folate coenzyme rau purine, thymidine thiab amino acid synthesis. Lub lactate counter-ion yog pharmacologically inert thiab ua hauj lwm tsuas yog los txhim kho aqueous solubility.

VimTrimethoprim Lactate hmoovtso tawm TMP uas khi cov kab mob DHFR kom nruj dua li cov tsiaj nyeg DHFR, nws depletes THF xaiv hauv cov kab mob, ntes DNA replication. Ib leeg bacteriostatic. Nws lub ntsiab lus txhais yog kev sib koom ua ke nrog sulfonamides: sulfonamides inhibit DHPS ntawm cov kauj ruam ua ntej folate, thaum TMP thaiv DHFR tom ntej - ib qho kev thaiv kab mob hloov pauv bacteriostasis rau cov kab mob bactericidal, nthuav dav spectrum thiab ua kom tsis muaj zog. Qhov zoo tshaj plaws cov ntaub so ntswg piv ~ 1:20 (TMP: sulfonamide), ua tiav nrog 1: 5 qhov ncauj tsau koob. Active tiv thaiv Gram-positive (Staphylococcus, Streptococcus, Listeria) thiab Gram -negative (E. coli, Klebsiella, Proteus, Salmonella, Pasteurella) cov kab mob. Lub raum excretion; kev hloov koob tshuaj hauv lub raum tsis zoo. Cov dej solubility siab ua rau siab -cov tshuaj txhaj tshuaj ntau npaum li cas (txog 40 mg/mL TMP) thiab cov tshuaj pleev qhov ncauj rau kev siv kws kho tsiaj.

Dab tsi yog Daim Ntawv Thov ntawm Trimethoprim Lactate Powder?

Veterinary Injectable Solutions: Thawj daim ntawv thov - cov dej solubility siab ua kom muaj cov tshuaj txhaj tshuaj ntau yam (xws li sulfadiazine 200 mg / mL + TMP 40 mg / mL) rau nyuj, npua, dev thiab miv.
Veterinary Oral Solutions & Suspensions: Dej- daim ntawv soluble rau palatable kua qhov ncauj, nrog rau equine qhov ncauj ncua kev kawm ntawv (xws li, EQUISUL-SDT sulfadiazine/TMP).
Cov kab mob ua pa ua pa: kab mob ua pa hauv plab (Pasteurella, Mannheimia), swine pleuropneumonia (Actinobacillus, Streptococcus suis), nqaij qaib thiab tus khub tsiaj ua pa.
Kab mob plab thiab tso zis: Colibacillosis, salmonellosis, pasteurellosis thiab kis kab mob urinary hauv cov tsiaj nyeg thiab tsiaj.
Potentiated Sulfonamide Combinations: Formulated nrog sulfadiazine, sulfadimethoxine, sulfamethoxazole thiab lwm yam sulfonamides rau dav -spectrum bactericidal kev ua.

Qhov txawv ntawm Trimethoprim Lactate thiab Trimethoprim (Dawb Base) yog dab tsi?

Feature	Trimethoprim Lactate	Trimethoprim (Dawb Base)
CAS	23256-42-0	738-70-5
Molecular Formula	C₁₇H₂₄N₄O₆	C₁₄H₁₈N₄O₃
Molecular Luj	380.40	290.32
Dej Solubility	~ 20 mg/ml (soluble)	Me ntsis soluble
Daim foos thawj koob tshuaj	Cov tshuaj txhaj tshuaj, kua qhov ncauj	Cov ntsiav tshuaj, capsules, hmoov
Melting Point	170-172 degrees	199-203 degree
Antibacterial Activity	Zoo tib yam (lactate yog inert counter-ion)	Ib yam
Kev siv Veterinary	Kev txhaj tshuaj & tshuaj qhov ncauj nyiam dua	Oral ntsiav tshuaj / hmoov
Hom Concentration	Txog li 40 mg / mL TMP hauv kev txhaj tshuaj	Standard koob tshuaj qhov ncauj

Trimethoprim Lactate Sib piv nrog lwm cov dej li cas -Soluble Antibacterial Salts?

Feature	Trimethoprim Lactate	Sulfadiazine Sodium	Enrofloxacin Hydrochloride
CAS	23256-42-0	547-32-0	112732-17-9
Chav kawm	Diaminopyrimidine	Sulfonamide	Fluoroquinolone
Hom phiaj	DHFR	DHPS	DNA gyrase
Dej Solubility	Siab (20 mg / ml)	Siab	Siab
Kev siv thawj zaug	Kev txhaj tshuaj Veterinary (nrog sulfonamide)	Veterinary txhaj / UTI	Veterinary dav -spectrum
Synergy Partner	Sulfonamides (ib ntus blockade)	Trimethoprim	Tsis muaj
Cov kab mob bactericidal	Nrog sulfonamide (ib leeg zoo li qub)	Nrog TMP (ib leeg zoo li qub)	Yog lawm
Hom ntawv	Txhaj tshuaj	Txhaj tshuaj / qhov ncauj	Txhaj tshuaj / qhov ncauj

Trimethoprim Lactate Powder Ua li cas?

Trimethoprim Lactate hmoovyog tsim los ntawm thawj synthesizing dawb trimethoprim, ces tsim cov lactate ntsev ntawm acid- puag cov tshuaj tiv thaiv nrog lactic acid, ua raws li purification thiab crystallization.

Raw Khoom QC → Dawb Trimethoprim Synthesis (Condensation + Reduction) → Lactic Acid Salt Formation → Purification (Recrystallization) → Qhuav → Milling → Kawg QC → Ntim

HDM BIO tswj kev tsim cov ntsev tseem ceeb, crystallization thiab ziab kom tsis txhob muaj qhov purity zoo ib yam, dej solubility thiab batch zoo.

Cov Lus Qhia Zoo

Cov khoom kuaj	Txuj	Yam tshwm sim
Qhov tshwm sim	Dawb rau tawm -dawb hmoov	Zoo ib yam
Assay (HPLC, as TMP)	Ntau dua lossis sib npaug li 98.0%	99.0%
Tus Kheej (IR)	Ua raws li tus qauv siv	Kev lees paub
Melting Point	170-172 degrees	171 degree
Dej Solubility	20 mg / ml, ntshiab tov	Ua raws
Poob rau ziab	Tsawg dua lossis sib npaug li 0.5%	0.2%
Residue ntawm Ignition	Tsawg dua lossis sib npaug li 0.1%	Ua raws
Hnyav Hlau	Tsawg dua los yog sib npaug li 10 ppm	Ua raws
Arsenic	Tsawg dua lossis sib npaug li 2 ppm	Ua raws
Yam khoom muaj feem	Nyob rau hauv specification	Hla
Residual Solvents	Nyob rau hauv specification	Hla
Cov ntsiab lus ntawm lactic acid	Stoichiometric (1: 1)	Kev lees paub

Cov Kev Tswj Xyuas Zoo Ua Li Cas rau Trimethoprim Lactate Powder?

Txhua batch tau dhau los ua ntau yam -cov kauj ruam tswj kom zoo ua ntej tso tawm kom paub tseeb tias tus kheej, purity, ntsev stoichiometry thiab dej solubility.

Raw Material QC → Hauv -Kev Tswj Xyuas Txheej Txheem → HPLC Assay (raws li TMP) → IR Identity Verification → Melting Point Determination → Water Solubility Test → Lactic Acid Content Assay → Related Substances (HPLC) → Loss on Drying → Heavy Metals → Arsenic Resolution → Arsenic Resolution Kawg Batch Tso Tawm

Cov kev ntsuam xyuas tseem ceeb suav nrog kev txheeb xyuas los ntawm infrared (IR) spectroscopy, HPLC cov ntsiab lus tshuaj ntsuam xyuas (qhia raws li trimethoprim), kev txiav txim siab ntawm melting point, dej solubility verification (20 mg/mL clear solution), lactic acid stoichiometric content assay, ntsig txog tshuaj ntsuam xyuas, poob ntawm kev ziab, hnyav hlau daws teeb meem, thiab resignue residue. Txhua qhov kev lag luam batch tau txais kev txhawb nqa los ntawm ib pawg -COA tshwj xeeb thiab cov ntaub ntawv txheeb xyuas cuam tshuam rau QC tuaj thiab cov khoom tsim nyog.

Dab tsi cuam tshuam rau Trimethoprim Lactate Powder Bulk Nqe?

Trimethoprim Lactate Powder bulk pricing yog tsav los ntawm ntau yam tseem ceeb:

Synthesis & Salt Formation Nqis: Ntau- kauj ruam dawb trimethoprim synthesis ntxiv rau lactic acid ntsev tsim thiab recrystallization ncaj qha cuam tshuam rau kev tsim cov nqi.
Purity & Qib: Cov purity siab dua (Ntau dua lossis sib npaug li 99%) thiab cov kws kho mob -qib pawg tswj hwm tus nqi tshaj qib tus qauv.
Dej Solubility Specification: Cov khoom pov thawj tau lees paub kom ua tau raws li 20 mg / mL cov txheej txheem solubility rau kev txhaj tshuaj tuaj yeem nqa tus nqi.
Kev Tswj Xyuas Kev Ua Tau Zoo & Daim Ntawv Pov Thawj: GMP- qauv API batch nrog DMF/CEP thiab COA zoo ib yam xav tau tus nqi siab dua.
Order Volume: Loj -scale veterinary pharmaceutical daim ntawv cog lus tau txais steeper ib -kilogram luv nqi tshaj me me -batch xaj.
Logistics & Geography: Txias cia / lub teeb - tiv thaiv kev ntim khoom thiab kev lis kev cai ua raws ntxiv rau tus nqi tsaws.

Hu rau HDM BIO rau cov lus hais tam sim no thiab ntim-raws li tus nqi.

Vim li cas thiaj xaiv HDM BIO li koj tus kws kho mob Trimethoprim Lactate Powder Supplier?

High-purity (Ntau dua lossis sib npaug li 98% / raug 99%) dej-soluble trimethoprim lactate rau cov kws kho tsiaj tshuaj txhaj tshuaj thiab qhov ncauj formulations
Kev txheeb xyuas 20 mg/mL dej solubility - zoo tagnrho rau siab -concentration injectable solutions
Tib yam tshuaj tiv thaiv kab mob ua rau dawb TMP nrog cov qauv yooj yim dua
GMP -ua raws li kev tsim khoom, ISO & HACCP tau ntawv pov thawj zoo
Tag nrho batch traceability thiab ua tiav cov ntaub ntawv (COA, MSDS, HPLC)
Kev xa khoom yooj yim: kilogram qauv mus rau tuj - qib xaj ntau
Kev xa tawm thoob ntiaj teb mus rau 70+ lub teb chaws nrog kev txhawb nqa tag nrho

Ntim Ntim, Shipping & Cia

Ntim: Cov hnab ntawv rau cov qauv thiab cov dej noo-cov ntaub ntawv pov thawj fiber ntau rau kev txiav txim ntau.
Custom Packaging: OEM labeling muaj.
Cov ntaub ntawv xa khoom: COA, MSDS / SDS, daim ntawv them nqi lag luam, cov ntawv ntim khoom thiab cov ntaub ntawv kev lis kev cai muaj raws li kev txiav txim siab.
Cia: Khaws nruj nreem kaw rau hauv qhov chaw txias, qhuav, lub teeb - tiv thaiv ib puag ncig. Lub neej txee: 24 lub hlis.
Kev tuav: Rau cov khoom siv raw khoom siv xwb; tsis yog rau kev tswj xyuas kev kho mob ncaj qha.

Cov lus nug nquag nug txog Trimethoprim Lactate Powder

Q1: Trimethoprim Lactate Powder yog dab tsi?

A: Cov dej -soluble lactate ntsev ntawm trimethoprim (TMP), diaminopyrimidine DHFR inhibitor. Nws lub siab aqueous solubility (~ 20 mg / mL) ua rau nws nyiam daim ntawv rau veterinary txhaj tshuaj thiab kua qhov ncauj.

Q2: Tus lej CAS yog dab tsi?

A: 23256-42-0.

Q3: Trimethoprim lactate txawv li cas trimethoprim dawb?

A: Cov tshuaj tua kab mob zoo ib yam - lactate yog ib qho inert counter-ion. Qhov sib txawv tseem ceeb yog dej solubility: ~ 20 mg / mL rau lactate ntsev vs me ntsis soluble rau lub hauv paus dawb, ua rau daim ntawv lactate haum rau kev txhaj tshuaj thiab qhov ncauj daws.

Q4: Dab tsi yog trimethoprim lactate siv rau?

A: Feem ntau cov tshuaj tua tsiaj thiab cov kua hauv qhov ncauj tsim nrog sulfonamides (xws li sulfadiazine / TMP 200/40 mg / mL txhaj) rau cov kab mob ua pa, GI thiab tso zis hauv nyuj, npua, dev, miv, nees thiab nqaij qaib.

Q5: Cov ntaub ntawv twg yog muab rau txhua pawg?

A: Batch-cov ntawv qhia tshwj xeeb COA, HPLC, IR cov ntaub ntawv tus kheej, cov ntaub ntawv melting point, dej solubility test, lactic acid cov ntsiab lus, MSDS / SDS thiab cov ntaub ntawv xa tawm.

Q6: Dab tsi purity koj muab?

A: Standard Ntau dua lossis sib npaug rau 98% HPLC (raws li trimethoprim); raug batch tshwm sim 99%. USP/EP-qib muaj nyob rau ntawm kev thov.

Q7: Kuv tuaj yeem yuav nws li cas los ntawm Tuam Tshoj?

A: HDM BIO muab cov khoom loj Trimethoprim Lactate Powder nrog batch COA thiab kev txhawb nqa thoob ntiaj teb.

Q8: Trimethoprim Lactate Powder nqi ntau npaum li cas?

A: Tus nqi ntau yog nyob ntawm tus nqi sib xyaw / ntsev tsim, purity / qib, solubility specification, kev tswj hwm, kev txiav txim ntim thiab kev xa khoom. Hu rau HDM BIO rau cov lus hais tam sim no.

Q9: Puas muaj kev txhawj xeeb txog kev nyab xeeb?

A: Trimethoprim feem ntau zam tau zoo, tab sis cov koob tshuaj ntau / ntev yuav ua rau folate tsis txaus (tswj tau nrog folic acid). Feem ntau cov kev phiv loj heev hauv potentiated sulfonamide therapy yog tshwm sim los ntawm sulfonamide tivthaiv. Kev kho koob tshuaj yuav tsum tau nyob rau hauv lub raum tsis ua hauj lwm. Tsis yog rau kev tswj xyuas kev kho mob ncaj qha.

Q10: Puas yog lactate ntsev haum rau tib neeg siv?

A: Txawm hais tias cov khoom muaj txiaj ntsig zoo ib yam, trimethoprim lactate feem ntau yog siv hauv cov tshuaj tua tsiaj. Tib neeg formulations feem ntau siv dawb trimethoprim hauv ntsiav tshuaj daim ntawv. Siv raws li kev cai tswj kev cai.