Amikacin Sulfate API CAS 39831-55-5|Ntau dua lossis sib npaug rau 98% Veterinary Antibiotic Supplier Tuam Tshoj

Cov Ntsiab Lus Muag

✓ Semi-Synthetic Aminoglycoside - 30S Ribosome Irreversible Binding

✓ L-AHBA Side Chain - Resistant Bacterial Inactivating Enzymes (AAC/APH/ANT)

✓ Active Tawm tsam Gentamicin-Resistant Gram-Negative Strains

✓ Concentration-Dependent Bactericidal + Post-Cov nyhuv tshuaj tua kab mob

✓ Broad Gram -Negative Spectrum incl. Pseudomonas + Staphylococcus

✓ Dej-Soluble Sulfate ntsev - IM/IV Injectable Formulation Npaj

Amikacin Sulfate Powder yog dab tsi?

Amikacin Sulfate hmoovyog sulfate ntsev ntawm amikacin, ib nrab -synthetic aminoglycoside tshuaj tua kab mob muab tau los ntawm kanamycin A. Nws tshwj xeeb L-AHBA sab saw txhim khu kev ruaj ntseg tiv thaiv ntau aminoglycoside-inactivating enzymes, tso cai rau kev ua si tawm tsam ntau Gram-cov kab mob tsis zoo rau lwm cov aminoglycoside.

Hauv kev siv tshuaj kho tsiaj thiab tshuaj, nws yog siv los ua cov khoom siv raw rau cov qauv tsim cov kab mob uas muaj kab mob loj heev, tshwj xeeb tshaj yog tshwm sim los ntawm Gram- cov kab mob tsis zoo xws liEscherichia coli, PseudomonasthiabKlebsiella. Vim lub qhov ncauj tsis zoo, nws feem ntau tsim los rau hauv cov tshuaj txhaj tshuaj. Raws li nrog rau lwm cov aminoglycosides, kev tswj hwm nruj thiab kev tswj xyuas tsim nyog yuav tsum tau ua vim tias qhov raug ntau dhau tuaj yeem cuam tshuam nrog nephrotoxicity thiab ototoxicity txaus ntshai.

Amikacin Sulfate hmoov ua haujlwm li cas?

Amikacin Sulfate hmoovexerts nws cov kab mob bactericidal los ntawm irreversibly khi rau 30S ribosomal subunit, cuam tshuam cov kab mob protein synthesis. Qhov kev sib cuam tshuam no ua rau mRNA mis nyeem tsis zoo thiab tsim cov protein ntau txawv txav, ua rau cov membrane puas thiab cov kab mob cell tuag.

Cov molecule nkag mus rau Gram-cov kab mob tsis zoo los ntawm lub zog- nyob ntawm txoj kev thauj mus los thiab tswj kev ua haujlwm tawm tsam ntau cov aminoglycoside- cov kab mob resistant vim nws cov L-AHBA sab saw, uas txo qis kev cuam tshuam rau cov aminoglycoside ntau - inactivating enzymes. Nws cov concentration-nyob ntawm kev tua thiab tom qab- cov tshuaj tua kab mob ua rau nws muaj txiaj ntsig tiv thaiv Gram cov kab mob tsis zoo- cov kab mob tsis zoo.

Dab tsi yog Daim Ntawv Thov ntawm Amikacin Sulfate Powder?

Equine Gram- Kab mob tsis zoo: Kev kho kab mob E. coli, Pseudomonas thiab Klebsiella kab mob hauv nees (uterine, ua pa, kab mob hauv lub cev thiab sib koom tes), suav nrog cov kab mob uas tiv taus gentamicin.
Kab mob Canine & Feline: Siv rau cov kab mob Gram loj heev- tsis zoo ntawm cov kab mob hauv cov zis, ntawm daim tawv nqaij, cov nqaij mos, cov hlab ntsws thiab cov hlab ntsha, tshwj xeeb tshaj yog thaum kab lis kev cai thiab rhiab heev qhia txog kev tiv thaiv thawj - kab mob.
Multidrug-Resistant Gram- Cov Kab Mob Tsis Zoo: Ua haujlwm thaum qhov kev kuaj pom tseeb pom kev ua haujlwm tawm tsam Pseudomonas aeruginosa, Enterobacter, Proteus, Serratia lossis Acinetobacter hom resistant rau lwm cov aminoglycosides.
Kab mob Staphylococcus: Ua haujlwm tawm tsam qee yam kab mob Staphylococcus, feem ntau ua ke nrog beta -lactam rau kev sib koom ua ke ntawm cov kab mob bactericidal.
Tshuaj pleev ib ce / Otic Formulations: Incorporated rau hauv compounded pob ntseg thiab tshuaj pleev npaj rau resistant Pseudomonas otitis externa nyob rau hauv dev.

Dab tsi yog qhov txawv ntawm Amikacin Sulfate thiab Gentamicin Sulfate?

Feature	Amikacin Sulfate	Gentamicin Sulfate
CAS	39831-55-5	1405-41-0
Molecular Formula	C₂₂H₄₇N₅O₂₁S₂	C₂₁H₄₃N₅O₇·xH₂SO₄
Molecular Luj	781.76	~ 477.6 (hauv paus)
Keeb kwm	Semi-synthetic (kanamycin A + L-AHBA)	Ntuj (Micromonospora)
Enzyme Resistance	Siab (L-AHBA sab saw)	Tsawg (yuav raug rau ntau AAC / APH / ANT)
Gentamicin-Resistant Strains	nquag nquag	Resistant
Pseudomonas Kev Ua Si	Yog lawm	Yog lawm
Nephrotoxicity	Nruab nrab	Nruab nrab - siab
Ototoxicity	Nruab nrab	Nruab nrab - siab
Hom kev siv	Thib ob - kab / kab mob tiv taus	Thawj - kab broad Gram-negative

Amikacin Piv nrog rau lwm cov Veterinary Aminoglycosides li cas?

Feature	Amikacin	Gentamicin	Tobramycin	Neomycin	Apramycin
CAS	39831-55-5	1405-41-0	79645-27-5	1404-04-2	65710-07-8
Semi/Natural	Semi-synthetic	Ntuj	Ntuj	Ntuj	Ntuj
Enzyme Resistance	Siab	Tsawg	Nruab nrab	Tsawg	Nruab nrab
Pseudomonas	Yog lawm	Yog lawm	Yog (zoo tshaj)	Tsis muaj zog	Tsis muaj zog
Qhov ncauj nqus	Tsis tsim nyog	Tsis tsim nyog	Tsis tsim nyog	Tsis tsim nyog	Tsis tsim nyog
Thawj Txoj Kev	IM/IV	IM/IV	IM/IV	Qhov ncauj / tshuaj pleev ib ce	Qhov ncauj (feed)
Kev siv Veterinary	Nees, dev, miv	Txhua hom	dog, cat	Txhua yam (tshwj xeeb)	Swine, nyuj

Amikacin Sulfate Powder Ua li cas?

Amikacin Sulfate hmoovyog tsim los ntawm semi-synthetic hloov kho ntawm kanamycin A: xaiv acylation ntawm C-1 amino pawg nrog L-AHBA, ua raws li purification, sulfate ntsev tsim thiab sterile / non-sterile ua.

Raw Material QC → Kanamycin A Starting Material → Selective N-Acylation (L-AHBA) → Amikacin Dawb Base → Purification (Ion Txauv / Chromatography) → Sulfate ntsev tsim → Crystallization → Qhuav → Milling → Final QC → Ntim

HDM BIO tswj qhov tseem ceeb acylation, purification, ntsev tsim thiab crystallization tsis ua kom muaj zog zoo ib yam, purity thiab batch zoo.

Cov Lus Qhia Zoo

Cov khoom kuaj	Txuj	Yam tshwm sim
Qhov tshwm sim	Dawb rau tawm -dawb hmoov	Zoo ib yam
Potency (Bioassay)	Ntau dua lossis sib npaug li 900 ug / mg	940 ug/mg
Kev ntsuam xyuas (HPLC)	Ntau dua lossis sib npaug li 98%	99.0%
Tus Kheej (IR)	Ua raws li tus qauv siv	Kev lees paub
Kev sib hloov tshwj xeeb	+76℃rau +84 degree	+80 degree
pH (1% tov)	6.0–7.5	6.8
Poob rau ziab	Tsawg dua lossis sib npaug li 5.0%	2.0%
Residue ntawm Ignition	Tsawg dua los yog sib npaug li 0.5%	Ua raws
Hnyav Hlau	Tsawg dua los yog sib npaug li 10 ppm	Ua raws
Yam khoom muaj feem	Nyob rau hauv specification	Hla
Endotoxin (qib sterile)	Nyob rau hauv specification	Hla

Qhov Kev Tswj Xyuas Zoo Ua Li Cas rau Amikacin Sulfate Powder?

Txhua pawg tau dhau los ua ntau yam -txoj kev tswj kom zoo ua ntej tso tawm kom paub tseeb tias tus kheej, muaj zog, purity thiab kev nyab xeeb.

Raw Material QC → Hauv -Kev Tswj Xyuas Txheej Txheem → HPLC Assay → IR Identity Verification → Microbiological Potency Assay → Specific Rotation → Related Substances (HPLC) → Loss on Drying → Heavy Metals → Residue on Ignition → pH Test → Endotoxin gradual (Sterile Endotoxin) Kawg Batch Tso Tawm

Cov kev ntsuas tseem ceeb suav nrog kev txheeb xyuas los ntawm infrared (IR) spectroscopy, HPLC active cov ntsiab lus kev soj ntsuam, microbiological potency assay (ug/mg), kev sib hloov, kev txheeb xyuas cov tshuaj, poob ntawm ziab, hnyav hlau txwv, residue ntawm ignition, pH, endotoxin (rau sterile qib) thiab residual hnyav testing. Txhua pawg lag luam tau txais kev txhawb nqa los ntawm ib pawg -COA tshwj xeeb thiab cov ntaub ntawv txheeb xyuas cuam tshuam rau QC tuaj thiab cov khoom tsim nyog.

Dab tsi cuam tshuam rau Amikacin Sulfate Powder Bulk Nqe?

Amikacin Sulfate Powder bulk pricing yog tsav los ntawm ntau yam tseem ceeb:

Synthesis Costs: Semi-kev hloov kho hluavtaws ntawm kanamycin A nrog L-AHBA, suav nrog kev xaiv acylation thiab purification, ncaj qha cuam tshuam rau cov nqi tsim khoom.
Purity & Qib: Ntau dua potency (Ntau dua lossis sib npaug li 900 ug / mg), qib tsis muaj menyuam thiab endotoxin-cov khoom siv tswj hwm tau them nqi tshaj qhov tsis yog- qib tsis muaj tshuaj lom neeg.
Kev Tswj Xyuas Kev Ua Tau Zoo & Daim Ntawv Pov Thawj: GMP- qauv API batch nrog COA zoo ib yam thiab ua tiav cov ntaub ntawv xa tawm xav tau tus nqi siab dua.
Order Volume: Loj -scale cov ntawv cog lus tshuaj tau txais steeper ib -kilogram luv nqi tshaj me me -batch tshwj xeeb xaj.
Logistics & Geography: Shipping nrug, txias - saw / lub teeb - kev tiv thaiv kev ntim khoom thiab kev lis kev cai ntxiv rau tus nqi tsaws.

Hu rau HDM BIO rau cov lus hais tam sim no thiab ntim-raws li tus nqi.

Vim li cas thiaj xaiv HDM BIO ua koj Amikacin Sulfate Powder Supplier?

High-purity (Ntau dua lossis sib npaug rau 98% / Ntau dua lossis sib npaug rau 900 ug / mg) semi- hluavtaws aminoglycoside nrog cov pov thawj enzyme-ua haujlwm profile

Active tiv thaiv gentamicin -tiv taus Gram- tsis zoo hom - qhov tseem ceeb thib ob- kab veterinary agent

Dej-soluble sulfate ntsev haum rau IM/IV txhaj tshuaj formulations

GMP -ua raws li kev tsim khoom, ISO & HACCP tau ntawv pov thawj zoo

Tag nrho batch traceability thiab ua tiav cov ntaub ntawv (COA, MSDS, HPLC, potency assay)

Flexible mov: gram qauv mus rau tuj - qib xaj ntau

Kev xa tawm thoob ntiaj teb mus rau 70+ lub teb chaws nrog kev txhawb nqa tag nrho

Ntim Ntim, Shipping & Cia

Ntim: Cov hnab ntawv rau cov qauv thiab cov dej noo-cov ntaub ntawv pov thawj fiber ntau rau kev txiav txim ntau.
Custom Packaging: OEM labeling muaj.
Cov ntaub ntawv xa khoom: COA, MSDS / SDS, daim ntawv them nqi lag luam, cov ntawv ntim khoom thiab cov ntaub ntawv kev lis kev cai muaj raws li qhov xav tau.
Cia: Khaws nruj nreem kaw rau hauv qhov chaw txias, qhuav, lub teeb - tiv thaiv ib puag ncig. Lub neej txee: 24 lub hlis.
Kev tuav: Rau cov khoom siv raw khoom siv xwb; tsis yog rau kev tswj xyuas kev kho mob ncaj qha.

Cov lus nug nquag nug txog Amikacin Sulfate Hmoov

Q1: Amikacin Sulfate hmoov yog dab tsi?

A: Cov sulfate ntsev ntawm amikacin, ib nrab -synthetic aminoglycoside tshuaj tua kab mob muab tau los ntawm kanamycin A nrog ib tug L-AHBA sab saw uas tiv thaiv kab mob inactivating enzymes, siv rau hnyav Gram- tsis zoo kab mob.

Q2: Tus lej CAS yog dab tsi?

A: 39831-55-5 (sulfate ntsev); amikacin dawb puag yog 37517-28-5.

Q3: Amikacin ua haujlwm li cas?

A: Nws irreversibly khi cov kab mob 30S ribosomal subunit, ua rau mRNA misreading thiab zus tau tej cov proteins uas cuam tshuam rau daim nyias nyias, ua rau concentration- nyob ntawm cov kab mob cell tuag.

Q4: Vim li cas amikacin nquag tawm tsam gentamicin - cov kab mob resistant?

A: Nws L-AHBA sab saw thaiv cov chaw sib txuas ntawm feem ntau aminoglycoside-inactivating enzymes (AAC, APH, ANT), khaws cia ribosomal nkag mus rau hauv hom uas degrade gentamicin.

Q5: Cov tsiaj twg yog amikacin siv rau?

A: Nees (E. coli, Pseudomonas, Klebsiella), dev thiab miv ( tso zis, tawv nqaij, ua pa, kab mob hauv lub cev), thiab lwm yam kab mob rau kab lis kev cai - lees paub resistant Gram - kab mob tsis zoo.

Q6: Cov ntaub ntawv twg yog muab rau txhua pawg?

A: Batch- tshwj xeeb COA, HPLC daim ntawv tshaj tawm, IR cov ntaub ntawv tus kheej, kev tshuaj xyuas microbiological potency, cov ntaub ntawv sib hloov, MSDS/SDS thiab cov ntaub ntawv xa tawm.

Q7: Dab tsi purity koj muab?

A: Txuj Loj dua lossis sib npaug rau 98% HPLC / Ntau dua lossis sib npaug rau 900 ug / mg potency. Sterile thiab qib siab dua muaj nyob rau ntawm kev thov.

Q8: Kuv tuaj yeem yuav nws li cas los ntawm Tuam Tshoj?

A: HDM BIO muab ntau Amikacin Sulfate Powder nrog batch COA thiab kev txhawb nqa thoob ntiaj teb.

Q9: Amikacin Sulfate Powder raug nqi ntau npaum li cas?

A: Tus nqi ntau yog nyob ntawm ib nrab- cov nqi sib txuas, purity/qib, kev tswj hwm kev tswj hwm, kev txiav txim ntim thiab kev xa khoom. Hu rau HDM BIO rau cov lus hais tam sim no.

Q10: Puas yog amikacin muaj kev nyab xeeb?

A: Amikacin muaj cov chav kawm - raug nephrotoxicity thiab ototoxicity txaus ntshai. Nws yog muab raws li kws kho tsiaj / kws tshuaj raw khoom nkaus xwb; Kev saib xyuas cov tshuaj kho mob thiab dej kom txaus yog pom zoo thaum siv tshuaj kho mob. Tsis yog rau kev tswj xyuas kev kho mob ncaj qha.