Sinapultide hmoov CAS 138531-07-4|High Purity KL-4 Peptide Surfactant Protein-B Mimic Supplier Tuam Tshoj

Core Muag Cov Ntsiab Lus

✅ Ntau dua lossis sib npaug li 98% HPLC Purity Salmon Calcitonin Powder nrog Batch-Specific COA Muaj

✅ Txheeb xyuas los ntawm HPLC, LC-MS thiab Kev Ntsuam Xyuas Cov Qauv rau Peptide Identity Confirmation

✅ Tuam Tshoj Peptide Chaw Tsim Tshuaj nrog Fmoc-SPPS Ntau Lawm & GMP-Compliant Quality System

✅ Tshwj xeeb hauv Complex 32-Mer Disulfide-Bonded Salmon Calcitonin Peptide Synthesis thiab Purification

✅ Ua tiav Cov Ntaub Ntawv Pob: COA, HPLC Chromatogram, LC-MS Report & MSDS

✅ Siv tau yooj yim los ntawm Kev Tshawb Fawb Cov Qauv rau Cov Khoom Muag Peptide Thoob Ntiaj Teb

Sinapultide Powder yog dab tsi?

Sinapultide hmoov, tseem hu ua KL-4 peptide, yog ib qho hluavtaws amphipathic 21-amino-acid linear peptide tsim los ua kom zoo li lub luag haujlwm helical ntawm tib neeg surfactant protein-B (SP-B). Nws muaj cov lysine-leucine motifs, muaj peev xwm cuam tshuam nrog phospholipid bilayers kom txo alveolar nto nro. Kev siv dav dav hauv pulmonary surfactant formulation R&D, kev tshawb fawb ntawm neonatal respiratory distress syndrome, mob ntsws raug mob (ALI) pharmacology, ntsws biophysics thiab peptide qauv-kev sib raug zoo kev tshawb nrhiav.

Tsim los ntawm optimized Fmoc solid-phase peptide synthesis ua ke nrog fragment-condensation zoo raws li peb cov GMP-aligned zoo system, pebSinapultide hmoovnruj me ntsis tswj deletion truncates, racemization impurities thiab hydrophobic aggregate by-products, securing raws li nto-active lom kev ua tau zoo thiab zoo heev batch-to-batch reproducibility. HDM BIO ua haujlwm thoob ntiaj teb biochemistry lub chaw soj nstuam, kws tshuaj R & D cov tuam txhab thiab cov chaw tsim tshuaj lom neeg, suav nrog milligram-theem kev tshawb fawb kuaj txog li kilogram-scale thoob ntiaj teb kev yuav khoom. Cov khoom siv peptide no tsuas yog txwv tsis pub siv rau kev tshawb fawb hauv chav kuaj thiab yuav tsum tsis txhob siv ncaj qha rau tib neeg kev tswj hwm kev kho mob.

Dab tsi yog Qhov Kev Ua Haujlwm Zoo ntawm Sinapultide Powder?

Txhua pawg tsim khoom ntawm Sinapultide tau dhau los kuaj ntau qib QC suav nrog HPLC, LC-MS thiab kev txheeb xyuas cov qauv hauv HDM BIO hauv tsev tshuaj ntsuam xyuas. Batch-specific COA yuav raug muab rau txhua qhov kev txiav txim yuav khoom.

Yam khoom	Specification	Kev tshwm sim
Qhov tshwm sim	Dawb rau tawm -dawb hmoov	Zoo ib yam
Purity (HPLC)	Ntau dua lossis sib npaug li 98%	99.88%
MS Identity	Raws li tus qauv siv	Kev lees paub
Xaus	Cosmetic raw khoom xav tau	Dhau

Sinapultide vs Lwm Pulmonary-Targeted Peptides

Rau cov neeg yuav khoom nrhiav lub ntsws-kev tshawb fawb peptide raw cov ntaub ntawv rau kev tshawb fawb txog kev ua pa, lub rooj sib piv qhia meej qhov sib txawv tseem ceeb rau kev xaiv cov khoom siv raw:

Khoom	Target Mechanism	Tus yam ntxwv	Daim Ntawv Thov Kev Tshawb Fawb Tseem Ceeb	CAS Nr
Sinapultide	Mimic SP-B, txo alveolar nto nro, cuam tshuam nrog phospholipids	21-mer amphipathic KL-4 rov qab linear peptide	Synthetic pulmonary surfactant development, neonatal mob ntsws qauv	138531‑07‑4
B-type Surfactant Peptide (Short SP-B fragment)	Nto-tension txo	15-mer hydrophobic peptide	In-vitro lipid-membrane kev sib cuam tshuam kev soj ntsuam	Kev cai
SP-C Peptide Analogs	Stabilize lipid monolayer	Hydrophobic helical peptide	Kev tshawb nrhiav surfactant biophysics	Kev cai

Tshooj lus no suav nrog cov lus tseem ceeb ntev: sinapultide KL4 peptide raw khoom, pulmonary surfactant research peptide, 21-mer amphipathic respiratory peptide.

Yuav ua li cas thiaj yuav Sinapultide hmoov los ntawm tus neeg muag khoom ntseeg siab?

Thaum muab khoomSinapultide hmoovrau pulmonary surfactant formulation thiab mob ntsws raug mob ua ntej kev tshawb fawb soj ntsuam, pab pawg R & D thiab cov neeg yuav khoom thoob ntiaj teb yuav tsum tau soj ntsuam tsib yam tseem ceeb kom tsis txhob muaj kev pheej hmoo ntawm cov khoom lag luam zoo:

HPLC purity validation: Paub meej ntau dua los yog sib npaug rau 98% HPLC purity nrog batch-specific COA thiab tag nrho impurity chromatogram; them nyiaj tshwj xeeb rau N-terminal / C-terminal truncated deletion fragments, racemized residues thiab hydrophobic aggregation-txog impurities uas impair lipid-interacting lom lom
Kev lees paub ntau txoj hauv kev: Peptide tus kheej raug lees paub los ntawm HPLC, LC-MS thiab kev txheeb xyuas cov qauv kom paub meej tias tag nrho-ntev 21-mer tiav cov amino-acid ib ntus; Kev txheeb xyuas cov amino-acid muaj pes tsawg leeg yog pom zoo
Ua kom tiav batch cov ntaub ntawv pob: lav txhua qhov kev txiav txim tau txais batch-specific COA, HPLC chromatogram, LC-MS daim ntawv qhia thiab MSDS kom txaus siab thoob ntiaj teb ntshuam kev lis kev cai clearance thiab kuaj xyuas cov cai.
Tsim nyog tsim system: Xaiv Tuam Tshoj peptide chaw tsim tshuaj paus nrog mature Fmoc-SPPS ntxiv rau fragment-condensation workflow thiab GMP-aligned zoo system, proven taug qab cov ntaub ntawv ntawm heev-repetitive hydrophobic-hydrophilic alternating sequence peptide synthesis
Ntiaj teb no saj zawg zog mov: Paub meej tias tus neeg muag khoom tuaj yeem xa ob qho tib si kev tshawb fawb me me thiab ntim loj thoob ntiaj teb kev txiav txim ntau peptide

HDM BIO muab kev tshawb fawb-qib Sinapultide nrog tag nrho cov ntaub ntawv pov thawj zoo, MOQ yoog raws rau kev sim kuaj batches thiab mus sij hawm ntev thoob ntiaj teb kev yuav khoom ntau.

Sinapultide Powder Nqe & Daim Ntawv Qhia Ntau Yam 2026

Yog tias koj tab tom nrhiav Sinapultide hmoov nqe, cov lus hais ntau thiab cov nqe lus xa khoom, thov xa mus rau cov ntaub ntawv tseem ceeb raws li hauv qab no:
Yam tsawg kawg nkaus Order Quantity: Flexible MOQ, milligram & gram-scale tshawb fawb qauv muaj; kilogram-theem thoob ntiaj teb cov khoom lag luam rau kev tshawb fawb txog kev lag luam
Sample Access: Cov qauv tshawb fawb sim rau kev soj ntsuam kuaj; hu rau pab neeg muag khoom kom tau txais cov qauv lus hais
Bulk Kilogram Pricing: Tiered pricing structure; loj bulk ntim coj kev sib tw chav tsev nqi
Lub Sijhawm Ua Haujlwm Ntau Lawm: Kev tuav tshwj xeeb yuav tsum tau ua kom rov ua tau ntau dua amphipathic 21-mer peptide nquag rau ntawm-resin aggregation; kev muag khoom yuav lees paub lub sijhawm tsim khoom raws sijhawm raws li kev nug
Shipping Options: kaw txias-pom zoo shipping thoob ntiaj teb; zam lub sijhawm ntev ntawm chav tsev kub; peb muab cov ntaub ntawv ua tiav (batch-specific COA, HPLC chromatogram, LC-MS daim ntawv qhia, MSDS, daim ntawv them nqi lag luam, cov ntawv ntim khoom) rau kev lis kev cai thoob ntiaj teb

Sinapultide Powder Procurement Guide for Global Buyers

Ua ntej muab kev txiav txim rau 21-mer amphipathic KL-4 peptide raw cov ntaub ntawv, pab pawg neeg yuav khoom thoob ntiaj teb yuav tsum ua tiav cov kauj ruam pov thawj no txhawm rau txo cov kev pheej hmoo:

Tus neeg muab khoom tsim nyog xyuas: Paub meej tias cov chaw tsim khoom muaj kev ywj pheej peptide-synthesis Rhiav thiab QC lab nrog GMP-aligned zoo system, kev ua haujlwm ntawm kev rov ua dua lysine-leucine sequence synthesis, resin aggregation suppression thiab truncation-impurity tswj
Kev tshuaj xyuas cov ntaub ntawv: Thov ua ntej xa khoom xa tuaj ua tiav pob ntawv suav nrog batch-specific COA, HPLC chromatogram, LC-MS daim ntawv qhia thiab MSDS; xav tau ntau txoj hauv kev peptide kev lees paub tus kheej, kuaj amino-acid muaj pes tsawg leeg thiab lwm yam-tshuaj lom neeg impurity profile suav nrog cov khoom tawg.
Kev pom zoo ntawm cov khoom: Paub meej tus qauv purity, qib endotoxin, impurity profile thiab txias cia yuav tsum phim koj cov kev sim tsim; aqueous reconstituted solution zoo li tsim peptide-lipid aggregates
MOQ & lub sij hawm lees paub: Txheeb xyuas cov qauv kev tshawb fawb / bulk peptide thoob ntiaj teb muaj, tshwj xeeb rov ua dua-ib ntu peptide ntau lawm lub voj voog thiab kev txiav txim-kho txoj cai
Shipping-cov ntaub ntawv lees paub: Xyuas kom tus neeg xa khoom tuaj yeem muab cov ntaub ntawv ua tiav los ua kom tau raws li cov kev xav tau ntawm koj cheeb tsam lub hom phiaj

Hais txog HDM BIO Sinapultide Manufacturing Capability

HDM BIO muaj ntau tshaj 10-xyoo kev txawj ntse nyob rau hauv Fmoc-SPPS peptide synthesis raws li GMP-txoj kev zoo system, tshwj xeeb nyob rau hauv complex heev-repetitive amphipathic peptide manufacturing.

Dedicated Fmoc-SPPS cov kab ntau lawm; txais yuav fragment-condensation synthetic lub tswv yim rau KL-4 rov ua ntu zus los txo cov kev pheej hmoo ntawm cov resin aggregation, txo qis kev tshem tawm truncates thiab racemization impurities; optimized cleavage raws tu qauv rau hydrophobic-hydrophilic alternating peptide
Lub chaw soj ntsuam ywj pheej nruab nrog HPLC, LC-MS thiab cov cuab yeej tshuaj ntsuam xyuas; Kev ua haujlwm tshwj xeeb rau kev lees paub tus kheej peptide, amino-acid muaj pes tsawg leeg validation thiab truncated-fragment impurity quantification
Peptide cov khoom xa tawm thoob ntiaj teb mus rau ntau dua 70 lub teb chaws, txhawb nqa tsev kawm ntawv labs, biotech startups thiab kws tshuaj R & D lub koom haum
Muaj peev xwm tsim tau txhua xyoo ruaj khov rau kev tshawb fawb-qib peptide raw cov ntaub ntawv, txhawb kev koom tes ua haujlwm ntev
Pab pawg kws tshaj lij tau paub txog hauv pulmonary-kev tshawb fawb peptide-series synthesis, aggregation-control process optimization thiab ntsig txog kev hloov kho analog.

Peb lub chaw tsim khoom peptide ua haujlwm rau Fmoc-SPPS cov kab ntau lawm, hauv tsev npaj-HPLC purification thiab ua tiav ntau qhov kev ntsuam xyuas kev ua haujlwm rau txoj haujlwm nyuaj amphipathic long-chain peptides.

Dab tsi kev sib tw muaj nyob rau hauv Sinapultide Synthesis & Production?

Sinapultide yog ib qho kev rov ua dua 21-mer amphipathic KL-4 peptide, alternating hydrophobic leucine thiab lysine residues zoo. Tswj cov txheej txheem resin aggregation, cumulative deletion-truncated impurities, amino-acid racemization thiab tsis zoo solubility thaum lub sij hawm purification yog core technical bottlenecks cais cov tuam txhab tsim nyog peptide los ntawm cov neeg muag khoom qis.

Cov teeb meem tseem ceeb ntawm kev tsim khoom:

- Kev rov ua dua Lys-Leu rov ua ntu zus tau yooj yim ua rau peptide saw aggregation ntawm cov khoom siv thaum lub sij hawm SPPS elongation, ua rau ntau qhov kev tshem tawm cov impurities uas nyuaj rau tshem tawm los ntawm cov pa HPLC.

- Alternating hydrophobic-hydrophilic residues ua rau tsis ruaj khov solubility profile; crude peptide qhia tsis zoo solubility nyob rau hauv ntau yam tsis zoo, ua kom purification nyuaj

- Kev pheej hmoo ntawm leucine thiab lysine racemization thaum lub sij hawm coupling thiab cleavage kauj ruam; racemized isomer impurities zoo ib yam li lub ntsiab-peak thiab nyuaj rau kev sib cais

- Ib qho kev xeem HPLC tsis txaus rau kev txiav txim zoo; multi-validation ntawm HPLC, LC-MS ntxiv rau cov amino-acid muaj pes tsawg leeg tsom xam yog yuav tsum tau kom lav tag nrho-ntev tsis tu ncua ib theem zuj zus rau pulmonary surfactant-txog functional biology assays

Sinapultide Powder Ua Haujlwm li cas hauv Kev Tshawb Fawb Kev Tshawb Fawb?

Raws li hluavtaws SP-B-mimicking KL-4 peptide,Sinapultide hmoovinserts rau hauv phospholipid bilayer sib dhos, reorganizes lipid-monolayer qauv thiab txo qis interfacial nto nro ntawm huab cua-kua interface. Nws ua haujlwm tseem ceeb hauv kev sim reagent rau SP-B mimic mechanism profiling, hluavtaws pulmonary surfactant formulation kev tshuaj ntsuam, mob ntsws-mob mob-tus qauv kev tshawb fawb thiab sinapultide analog qauv-kev sib raug zoo tshawb nrhiav. Tag nrho cov txheej txheem piav qhia tsuas yog txwv rau hauv vitro thiab pre-clinical tsiaj-kev tshawb fawb scenarios nkaus xwb.

Sinapultide Powder Ua li cas ntawm HDM BIO?

Sinapultide yuav tsum muaj kev tswj xyuas tag nrho rau kev rov ua cov txheej txheem fragment condensation, on-resin aggregation suppression, racemization tiv thaiv thiab solubility-optimized purification thoob plaws synthesis, cleavage, purification thiab lyophilization, ua nyob rau hauv peb GMP-zoo system.

Nyeem cov lus qhia ntsig txog: Disulfide-Containing Peptide API Manufacturing Guide|Fmoc SPPS Technology piav qhia

Ua kom tiav Sinapultide Powder Manufacturing Workflow

Raw-material QC ntawm Fmoc-amino-acid tsev blocks → Fragment synthesis ntawm KL-4 rov ntu → Kauj ruam-wise fragment condensation ntawm cov khoom resin nrog anti-aggregation optimized raws tu qauv → Resin cleavage & ntiaj teb no deprotection nrog racemization-suppression Crude-justlub system pre-scavenger → Tsis siv neeg qhov system → Multi-theem npaj-HPLC purification (tshem tawm truncated deletion fragments, racemized isomers & aggregate-related impurities) → Buffer-exchange rau lub hom phiaj ntsev-form hloov kho → Nqus lyophilization → Tag nrho multi-txoj kev QC kuaj (HMS, amino acid kev txheeb xyuas-LC- txheeb xyuas tus kheej endotoxin test) → Batch-specific COA tso tawm → Lub teeb-pov thawj, tsis muaj dej noo ntim ntim

QC Kev Tshawb Fawb Kev Ua Haujlwm

Cov khoom siv raw QC → In-process resin-aggregation & racemization risk monitoring → HPLC purity test → LC-MS molecular-weight & full-sequence verification → Supplementary amino-acid composition analysis for peptide identity confirmation → Truncated-fragment & isomer impurity → Metureative-quantity Residual-solvent & endotoxin nrhiav kom pom → Thaum kawg batch-tso tso cai pom zoo raws li GMP-txhim kho qhov zoo

Cov txheej txheem tseem ceeb

- Fragment-condensation synthetic workflow kom txo tau ntawm-resin aggregation rau cov repetitive KL-4 ib ntus - Tag nrho cov txheej txheem racemization-suppression parameter tswj kom txo tau cov stereoisomer impurities - Solubility-optimized tsis system rau crude peptide ua ntau thiab kev sib cais HP-P-preparative LC-resol cais cov structurally-zoo ib yam truncated fragments thiab racemized isomer impurities - Ntau theem kev lees paub tus kheej: HPLC, LC-MS ntxiv rau cov amino-acid muaj pes tsawg leeg tsom xam xyuas qhov ntev ntawm cov peptide - Lyophilized khoom ruaj khov khaws cia ntawm −20 degree; aqueous tov nws tus kheej peptide-lipid aggregation, aliquot thiab khaws cia ntawm -80℃tam sim ntawd tom qab reconstitution, tsis txhob rov qab khov-thaw mus.

Dab tsi yog Daim Ntawv Thov Tseem Ceeb ntawm Sinapultide Powder?

Pulmonary surfactant biophysics tshawb fawb: SP-B mimic mechanism assay, phospholipid-peptide membrane-interaction test, deg-tension ntsuas, sinapultide analog structure-activity-relationship exploration
Kev ua pa ua ntej kev kho mob R&D: Synthetic lung-surfactant prototype development, neonatal respiratory distress syndrome model evaluation, mob ntsws raug mob (ALI) pharmacological intervention study
Kev tshawb fawb txog kev xa tshuaj pulmonary: Peptide-pab lipid microbubble, liposome pulmonary-targeting delivery-system txhim kho
Peptide formulation development: Lyophilized-formulation feasibility research, sinapultide-muaj complex lipid-peptide system development
Biomedical reagent npaj: Laboratory siv cov qauv thiab kev sim-tswj reagents rau SP-B-tsev neeg surfactant peptide kev tshawb fawb
Complex heev-repetitive amphipathic-peptide-process-development kev tshawb fawb: 21-mer KL-4 rov peptide synthesis & aggregation-impurity-control benchmark compound

Vim li cas thiaj xaiv HDM BIO ua koj tus neeg muag khoom Sinapultide hmoov?

10+-xyoo Tuam Tshoj-raws li peptide-tsim kev paub nrog Fmoc-SPPS ntau lawm thiab GMP-ua raws li qhov system zoo
Tshwj xeeb muaj peev xwm rau complex 29-mer C-terminal-amidated sermorelin acetate peptide synthesis thiab purification, zoo txo sequence-deletion, methionine-oxidized by-products thiab de-amidated impurities
Txhua batch txhawb nqa los ntawm ntau qhov kev lees paub: HPLC, LC-MS thiab kev tshuaj xyuas cov qauv, xa nrog cov ntaub ntawv tshwj xeeb ua tiav pob - Ua tiav cov ntaub ntawv tsim khoom tsim tawm-ua kom tiav rau Sermorelin Acetate Powder
Lub peev xwm hloov tau thoob ntiaj teb: kev tshawb fawb cov qauv rau kilogram-scale bulk peptide xaj - Ntiaj teb no-export kev pab cuam npog ntau tshaj 70 lub teb chaws thoob ntiaj teb
Cov kws tshaj lij pab pawg txhawb nqa GHRH-tsev neeg peptide kev tshawb fawb thiab kev cai-analog synthesis kev sab laj

FAQs Txog Sinapultide Powder

Q: Qhov twg kuv tuaj yeem yuav Sinapultide hmoov los ntawm Tuam Tshoj?

A: HDM BIO yog cov chaw tsim khoom hauv Suav teb nrog Fmoc-SPPS & fragment-condensation ntau lawm thiab GMP-aligned zoo system, tshwj xeeb hauv complex 21-mer amphipathic KL-4 surfactant-mimic peptide. Peb muab high-puritySinapultide hmoovrau thoob ntiaj teb kws tshuaj R & D pab pawg thiab bioreagent chaw soj nstuam, hloov pauv thoob ntiaj teb los ntawm kev tshawb fawb cov qauv mus rau ntau peptide xaj.

Q: Cov ntaub ntawv dab tsi yuav tsum yog tus neeg tsim nyog Sinapultide muab?

A: Cov neeg muag khoom ntseeg siab yuav tsum muab cov ntaub ntawv ua tiav: batch-specific COA, HPLC chromatogram, LC-MS report & MSDS. Peptide tus kheej raug txheeb xyuas los ntawm HPLC, LC-MS thiab amino-acid muaj pes tsawg leeg tsom xam; truncated-fragment, racemized-isomer thiab endotoxin-testing cov ntaub ntawv muaj nyob rau ntawm kev thov.

Q: CAS tus naj npawb ntawm Sinapultide Powder yog dab tsi?

A: Tus lej CAS npe ntawm Sinapultide Powder yog 138531-07-4.

Q: Dab tsi purity qib ntawm Sinapultide hmoov koj tuaj yeem xa tuaj?

A: Txuj kev tshawb fawb-qib Ntau dua lossis sib npaug rau 98% HPLC purity. Txhua batch los nrog batch-specific COA thiab multi-txoj kev qhia tus kheej validation. Higher-purity specifications thiab surfactant-series custom-peptide-analog synthesis yog muaj rau kev sim tshwj xeeb.

Q: Yuav ua li cas lyophilized Sinapultide hmoov yuav khaws cia?

A: Khaws kaw ntawm -20 degree, kom deb ntawm lub teeb thiab noo noo. Ua nruj ua tsiv kom tsis txhob rov qab khov-thaw cycles. Aqueous reconstituted daws yog nquag mus rau amphipathic self-aggregation; npaj ib leeg-siv aliquots thiab khaws cia ntawm −80 degree, lub sij hawm ntev cia nyob rau hauv 2-8℃tsis pom zoo.

Q: Kuv puas tuaj yeem tau txais Sinapultide cov qauv tshawb fawb ua ntej yuav ntau?

A: Yog. Peb muab cov qauv tshawb fawb milligram-rau-gram-theem txuas nrog cov ntaub ntawv ua tiav pob rau kev soj ntsuam hauv chav kuaj.

Q: Dab tsi yog MOQ rau bulk Sinapultide hmoov thoob ntiaj teb xaj?

A: MOQ yog hloov tau raws li qib purity thiab ntim specifications. Peb txhawb nqa cov qauv tshawb fawb me me thiab cov ntim loj thoob ntiaj teb kev txiav txim siab peptide rau ntau qhov kev xav tau.

Q: Dab tsi yog qhov amino-acid sequence ntawm Sinapultide Powder?

A: H-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-OH (KL-4 rov motif).

Kev Tshawb Fawb Txog Kev Tshawb Fawb

Tshuaj xyuas los ntawm:

HDM BIO Peptide Technical Team

Kev txawj ntse:

Fmoc-SPPS peptide synthesis Complex long-chain aggregation-prone disulfide-bonded amylin-tsev neeg peptide manufacturing Multi-method peptide characterization: HPLC, LC-MS thiab kev txheeb xyuas cov qauv

Kho tshiab kawg: Lub Yim Hli 2026

Kev lees paub: Tag nrho cov ntsiab lus ntawm cov khoom lag luam ua haujlwm rau kev tshawb fawb kev kawm thiab cov khoom siv raw khoom siv xwb. Tsis yog siv rau tib neeg kev kho mob, kev kuaj mob lossis kev kho mob.